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depression

CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms.

Juhasz, G., D. Chase, E. Pegg, D. Downey, Z. Tóth, K. Stones, H. Platt, K. Mekli, A. Payton, R. Elliott, et al., "CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms.", Neuropsychopharmacology, vol. 34: Nature Publishing Group, pp. 2019–2027, February, 2009.
  • CNR1
  • depression
  • epistasis
  • gene × environment interaction
  • Haplotype
  • personality

Risk-Taking Behavior in a Gambling Task Associated with Variations in the Tryptophan Hydroxylase 2 Gene: Relevance to Psychiatric Disorders.

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Juhasz, G., D. Downey, N. Hinvest, E. Thomas, D. Chase, Z. Tóth, K. Lloyd-Williams, K. Mekli, H. Platt, A. Payton, et al., "Risk-Taking Behavior in a Gambling Task Associated with Variations in the Tryptophan Hydroxylase 2 Gene: Relevance to Psychiatric Disorders.", Neuropsychopharmacology, vol. 35: Nature Publishing Group, pp. 1109–1119, 2010.
  • depression
  • haplotype analysis
  • psychiatric disorders
  • risk taking
  • TPH2

The HTR1A and HTR1B receptor genes influence stress-related information processing.

Mekli, K., A. Payton, F. Miyajima, H. Platt, E. Thomas, D. Downey, K. Lloyd-Williams, D. Chase, Z. Tóth, R. Elliot, et al., "The HTR1A and HTR1B receptor genes influence stress-related information processing.", European Neuropsychopharmacology, vol. 21, issue 1: Elsevier B.V. and ECNP, pp. 129-139, 2011.
  • Anxiety
  • depression
  • HTR1A
  • HTR1B
  • Stress

The CREB1-BDNF-NTRK2 Pathway in Depression: Multiple Gene-Cognition-Environment Interactions.

Juhasz, G., J. S. Dunham, S. McKie, E. Thomas, D. Downey, D. Chase, K. Lloyd-Williams, Z. Tóth, H. Platt, K. Mekli, et al., "The CREB1-BDNF-NTRK2 Pathway in Depression: Multiple Gene-Cognition-Environment Interactions.", Biological Psychiatry, vol. 69, issue 8: Elsevier Inc. , pp. 762-771, 2011.
  • BDNF
  • childhood trauma
  • CREB1
  • depression
  • NTRK2
  • rumination

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